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Wei Chen (Peking University Health Science Center, Beijing)Oral Presentation
Background: TNBC accounts for 15-20% of breast cancers with aggressive behavior and poor prognosis.
Objective: To identify epigenetic modifications in ctDNA as non-invasive prognostic biomarkers.
Methods: Genome-wide methylation profiling of ctDNA from 245 TNBC patients using bisulfite sequencing, 36-month follow-up.
Results: 12 DMRs predicted PFS (HR=3.42, p<0.001). Methylation signature...
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